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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LASP1 All Species: 25.15
Human Site: T38 Identified Species: 42.56
UniProt: Q14847 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14847 NP_006139.1 261 29717 T38 H C E T C K M T L N M K N Y K
Chimpanzee Pan troglodytes XP_511445 391 42950 T168 H C E T C K M T L N M K N Y K
Rhesus Macaque Macaca mulatta XP_001085111 261 29741 T38 H C E T C K M T L N M K N Y K
Dog Lupus familis XP_851714 257 29048 T34 K A C F H C E T C K M T L N M
Cat Felis silvestris
Mouse Mus musculus Q61792 263 29976 T38 H C E T C K M T L N M K N Y K
Rat Rattus norvegicus Q99MZ8 263 29952 T38 H C E T C K M T L N M K N Y K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516545 118 13511
Chicken Gallus gallus Q01406 563 63311 D250 G K F G V Q T D R Q D K C A L
Frog Xenopus laevis Q6GM14 376 42749 G152 E S N R G N E G P Q G P V G S
Zebra Danio Brachydanio rerio NP_997801 234 26681 V12 C S R C N R V V Y P T E K V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8I7C3 657 74228 T38 K C T E C G M T L N M K T Y K
Honey Bee Apis mellifera XP_001121584 320 35562 I38 K C Q G C G M I L N M R T Y K
Nematode Worm Caenorhab. elegans P34416 335 37006 T40 K C T V C G M T L N M K N Y K
Sea Urchin Strong. purpuratus XP_797085 249 27176 K27 C L D K S W H K L C F K C E T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.7 98.4 94.6 N.A. 95.4 96.1 N.A. 41.7 21.3 21.8 68.5 N.A. 23.1 42.1 37.3 50.1
Protein Similarity: 100 66.7 99.2 95.7 N.A. 97.3 97.3 N.A. 43.6 30.5 38 75.4 N.A. 30.4 53.4 51 60.5
P-Site Identity: 100 100 100 13.3 N.A. 100 100 N.A. 0 6.6 0 0 N.A. 66.6 53.3 73.3 13.3
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. 0 13.3 0 20 N.A. 66.6 66.6 73.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % A
% Cys: 15 58 8 8 58 8 0 0 8 8 0 0 15 0 0 % C
% Asp: 0 0 8 0 0 0 0 8 0 0 8 0 0 0 0 % D
% Glu: 8 0 36 8 0 0 15 0 0 0 0 8 0 8 0 % E
% Phe: 0 0 8 8 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 0 15 8 22 0 8 0 0 8 0 0 8 0 % G
% His: 36 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 29 8 0 8 0 36 0 8 0 8 0 65 8 0 58 % K
% Leu: 0 8 0 0 0 0 0 0 65 0 0 0 8 0 8 % L
% Met: 0 0 0 0 0 0 58 0 0 0 65 0 0 0 8 % M
% Asn: 0 0 8 0 8 8 0 0 0 58 0 0 43 8 8 % N
% Pro: 0 0 0 0 0 0 0 0 8 8 0 8 0 0 0 % P
% Gln: 0 0 8 0 0 8 0 0 0 15 0 0 0 0 0 % Q
% Arg: 0 0 8 8 0 8 0 0 8 0 0 8 0 0 0 % R
% Ser: 0 15 0 0 8 0 0 0 0 0 0 0 0 0 8 % S
% Thr: 0 0 15 36 0 0 8 58 0 0 8 8 15 0 8 % T
% Val: 0 0 0 8 8 0 8 8 0 0 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 58 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _